Smart's career really started to take off in 2001. Proving herself to be a major sex-symbol, her topless scene in the comedy Road Trip was partially responsible for the film's runaway success. That same year, Smart appeared in the ensemble film Rat Race and in the indie Macbeth adaptation Scotland, PA. In 2003, she could be seen both on HBO's reality show Project Greenlight and in The Battle of Shaker Heights, the film that was documented on the series. Smart started off the following year with a bang, appearing in two hit films by the end of the first quarter, The Butterfly Effect and Stasky and Hutch.